WASHINGTON -- Hillary Clinton has been officially confirmed as secretary of state by way of a roll call vote in the U.S. Senate. The actual swearing-in is expected to be private.

Clinton's confirmation was held up Tuesday by a lone Republican senator. Sen. Jon Cornyn of Texas said important questions have yet to be answered about foreign donations to former President Bill Clinton's global foundation, and whether it presents a conflict of interest for his wife. Cornyn raised his concerns again during a Senate hearing this afternoon.

Former presidential rival Senator John McCain and Senator Susan Collins of Maine spoke in the former first lady's favor. McCain even asked for anonymous consent on Clinton's confirmation before the lunch break.

Other senators lavished praise on the former president's foundation, saying the Clintons should not be punished for continuing to help communities worldwide after leaving office.

While most spoke in support of Clinton, there were a handful of Republicans who questioned her values.

Governor David Paterson, who will appoint Clinton's replacement, objected to Cornyn's move.

"Senator Clinton was voted out of the committee 16-1. I don't think there is any need for any grandstanding or self promotion at the expense of her reputation," said Paterson. "She will be the next secretary of state."

Paterson said he has all but made up his mind of her replacement and is expected to announce his decision by Saturday. Caroline Kennedy is seen as one of the frontrunners for the job. Paterson said Tuesday he is considering Attorney General Andrew Cuomo and he also praised Congresswoman Kirsten Gillibrand.